Uncertainty in Pharmacology: Epistemology, Methods, and Decisions

Prof. Barbara Osimani is Associate Professor of Logic and Philosophy of Science at the Polytechnic University of the Marche and is currently heading an ERC project, which also runs at the Munich Center for Mathematical Philosophy, LMU: "Philosophy of Pharmacology: Safety, Statistical Standards, and Evidence Amalgamation".

She is interested in scientific inference in research contexts characterised by strategic behaviour and she is developing a "Formal Epistemology of Medicine" in order to analyse issues arising in medical research, with a special focus on the complex interaction of methodological, social and regulatory as well as ethical dimensions in medicine. She worked on the precautionary principle, evidence hierarchies, causal assessment of pharmaceutical harm, and statistical inference. Her recent papers analyse issues around philosophy of evidence (reliability, bias, reproducibility, coherence) from a Bayesian perspective. Within her ERC project: "Philosophy of Pharmacology: Safety, Statistical Standards, and Evidence Amalgamation" she developed a Bayesian framework for the integration of heterogenous items of evidence for the purpose of causal assessment of drug-induced harm ("E-Synthesis")

Dr. La Caze is a lecturer at the School of Pharmacy, University of Queensland. He completed his PhD in the philosophy of science at The University of Sydney. His research focusses on philosophy of science, philosophy of medicine and ethics. He is particularly interested in exploring philosophical approaches to challenges that arise in interpreting and applying biomedical research.