Single-Molecule/Entity Spectroscopy

· ACS In Focus Libro 1 · American Chemical Society
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Single-Molecule/Entity Spectroscopy is an indispensable resource for scientists interested in understanding single-molecule spectroscopy comprehensively. By presenting detailed information on the technique’s principles, discussing its diverse applications, and providing insights into future developments, researchers can acquire a holistic overview of this dynamic field without the need to consult an extensive array of individual papers. This primer bridges the gap between standard undergraduate coursework to practical implementation in the research lab for single-molecule spectroscopy.

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Anne Myers Kelley (née Anne B. Myers) grew up in Riverside, California and earned a B.S. in chemistry from UC Riverside. She earned her Ph.D. in biophysical chemistry at UC Berkeley working with Richard A. Mathies on resonance Raman studies of the photophysics of bacteriorhodopsin and conjugated polyenes. After a postdoctoral stint doing ultrafast spectroscopy and dynamics at the University of Pennsylvania with Robin M. Hochstrasser, she joined the faculty at the University of Rochester in 1987. She was introduced to single-molecule spectroscopy during a sabbatical year (1992–93) with W. E. Moerner at the IBM Almaden Research Center, where she published the first vibrationally resolved single-molecule fluorescence spectra. After marrying David F. Kelley in 1999, she moved to Kansas State University for four years and then became one of the founding faculty at the new UC Merced campus in 2003. Her research has focused predominantly on studying the photophysics of molecules and semiconductor nanocrystals using mainly resonance Raman methods. She is the author of more than 160 peer-reviewed publications as well as a monograph, “Condensed-Phase Molecular Spectroscopy and Dynamics” (Wiley), now in its second edition. A runner for most of her adult life, she qualified for the U.S. Olympic Trials in the marathon in 1992.


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