Primary sclerosing cholangitis

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Sclerosing cholangitis is a chronic, fibrotizing and constrictive inflammation of the biliary ducts that progresses slowly and leads to cholestatic liver damage, to cirrhosis and in some patients to cholangiocarcinoma.E.g. in the Nordic countries, the prevalence of sclerosing cholangitis is particularly high and it is the most common indication for liver transplantation.

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