Medicinal Chemistry for Practitioners
07/2020 · John Wiley & Sons
Livro eletrónico
416
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Presenting both a panoramic introduction to the essential disciplines of drug discovery for novice medicinal chemists as well as a useful reference for veteran drug hunters, this book summarizes the state-of-the-art of medicinal chemistry. It covers key drug targets including enzymes, receptors, and ion channels, and hit and lead discovery. The book hen surveys a drug's pharmacokinetics and toxicity, with a solid chapter covering fundamental bioisosteres as a guide to structure-activity relationship investigations.
Acerca do autor
JIE JACK LI, PHD has practiced medicinal chemistry since 1997 at Pfizer, BMS, and Revolution Medicines, respectively, with a four-year sojourn at the University of San Francisco as an Associate Professor, teaching medicinal and organic chemistry. He is currently a vice president at ChemPartner, splitting his time between San Francisco and Shanghai. He has authored or edited 30 books and many of those were published by Wiley, including Drug Discovery: Practices, Processes, and Perspectives, Innovative Drug Synthesis, Modern Drug Synthesis, The Art of Drug Synthesis, and Contemporary Drug Synthesis.
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