Integrative Omics: Concept, Methodology, and Application

Manish Kumar Gupta · Pramod Katara · Sukanta Mondal · Ram Lakhan Singh

2024年5月 · Elsevier

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Integrative Omics: Concepts, Methodology and Applications provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference includes a range of chapters in a systemic 'step by step' manner, which begins with the basic concepts from Omic to Multi Integrative Omics approaches, followed by their full range of approaches, applications, emerging trends, and future trends. All key areas of Omics are covered including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics as well as omics technology policy and society research. Integrative Omics: Concepts, Methodology and Applications highlights the recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science. The book bridges the gap between biological sciences, physical sciences, computer science, statistics, data science, information technology and mathematics by presenting content specifically dedicated to mathematical models of biological systems. - Provides a holistic, integrated view of a defining and applying network approach, integrative tools, and methods to solve problems for rationalization of genotype to phenotype relationships - Offers an interdisciplinary approach to Databases, data analytics techniques, biological tools, network construction, analysis, modeling, prediction and simulation of biological systems leading to 'translational research', i.e., drug discovery, drug target prediction, and precision medicine - Covers worldwide methods, concepts, databases, and tools used in the construction of integrated pathways

作者简介

Dr. Manish Kumar Gupta is Associate Professor in the Department of Biotechnology at Uttar Pradesh. Dr. Gupta has published more than twelve research papers, published one edited book, five book chapters and given more than twenty-seven invited lectures. Dr. Gupta is life member of various academic societies such as Federation of Asian Biotechnology Association (FABA), Association of Microbiologist of India (AMI), Society of Environmental Sustainability (Founder member) and Indian Science Congress Association (ISCA). Dr. Gupta’s focus of the research work is to extract the key regulatory elements participating in the disease pathways through integrative biology approach. To investigate those, biological tools & databases with big scale data sets generated by state-of-the-art high-throughput technology integrated for computational analysis.

Pramod Katara is an Assistant Professor at the Centre of Bioinformatics, University of Allahabad. He has 14 years of teaching and research experience. He has published several peer-reviewed papers and has authored several book chapters. He is a member/life member of several national and international scientific societies and attended many symposia/conferences at national and international levels and presented invited lectures/papers there as well as chairing sessions. He has been actively working in the field of bioinformatics to solve various biological issues with the help of computational omics approaches. His current research is focused on the population-specific human genome and transcriptome analysis to predict the pharmacogenomic variant and solve pharmacogenomics related issues).

Dr. Sukanta Mondal is currently working as Principal Scientist, Physiology Division, ICAR-National Institute of Animal Nutrition and Physiology. His major research interests involve cloning, characterization and expression of genes regulating early embryonic loss, molecular characterization and expression of hormone receptors, impact of stress on maternal recognition of pregnancy etc. He has published over 130 research publications in various National/International journals and presented more than 30 papers at various National/International Conferences. He has delivered invited lectures in different conference throughout the country and abroad. He is Associate Editor of journals viz., American Journal of Biochemistry and Molecular Biology, Asian Journal of Biotechnology, Asian Journal of Cell Biology, Current Research in Poultry Science and Biotechnology etc.

Professor Ram Lakhan Singh is Vice-Chancellor of Nilamber-Pitamber University, Medininagar, India. He held position of Professor and Chair of Biochemistry at Dr. Rammanohar Lohia Avadh University, Ayodhya, India prior to joining this assignment. He has 31 years of experience as teacher and 39 years as researcher in the area of Environmental and Nutraceutical Biochemistry. Professor Singh published more than 87 research papers, written 17 book chapters and edited 6 books published by Springer, CRC and Elsevier. He guided 25 PhD students and has been invited as editorial board member of International journals. He has been awarded IUTOX Senior Fellowship in 2007 and admitted to the Fellowships of the Society of Toxicology in 2011 and Academy of Environmental Biology in 2015.