Data Science for Genomics

Amit Kumar Tyagi · Ajith Abraham

Nov. 2022 · Academic Press

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Data Science for Genomics presents the foundational concepts of data science as they pertain to genomics, encompassing the process of inspecting, cleaning, transforming, and modeling data with the goal of discovering useful information, suggesting conclusions and supporting decision-making. Sections cover Data Science, Machine Learning, Deep Learning, data analysis, and visualization techniques. The authors then present the fundamentals of Genomics, Genetics, Transcriptomes and Proteomes as basic concepts of molecular biology, along with DNA and key features of the human genome, as well as the genomes of eukaryotes and prokaryotes. Techniques that are more specifically used for studying genomes are then described in the order in which they are used in a genome project, including methods for constructing genetic and physical maps. DNA sequencing methodology and the strategies used to assemble a contiguous genome sequence and methods for identifying genes in a genome sequence and determining the functions of those genes in the cell. Readers will learn how the information contained in the genome is released and made available to the cell, as well as methods centered on cloning and PCR. - Provides a detailed explanation of data science concepts, methods and algorithms, all reinforced by practical examples that are applied to genomics - Presents a roadmap of future trends suitable for innovative Data Science research and practice - Includes topics such as Blockchain technology for securing data at end user/server side - Presents real world case studies, open issues and challenges faced in Genomics, including future research directions and a separate chapter for Ethical Concerns

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Dr. Amit Kumar Tyagi is Assistant Professor and Senior Researcher at Vellore Institute of Technology (VIT), Chennai, India. His current research focuses on Machine Learning with Big Data, Blockchain Technology, Data Science, Cyber Physical Systems, Smart and Secure Computing and Privacy. He has contributed to several projects such as “AARIN and “P3-Block to address some of the open issues related to the privacy breaches in Vehicular Applications (such as Parking) and Medical Cyber Physical Systems. He received his Ph.D. Degree from Pondicherry Central University, India. He is a member of IEEE.

Dr. Ajith Abraham is a Pro Vice-Chancellor at Bennette University. He is the director of Machine Intelligence Research Labs (MIR Labs), Australia. MIR Labs are a not-for-profit scientific network for innovation and research excellence connecting industry and academia. His research focuses on real world problems in the fields of machine intelligence, cyber-physical systems, Internet of things, network security, sensor networks, Web intelligence, Web services, and data mining. He is the Chair of the IEEE Systems Man and Cybernetics Society Technical Committee on Soft Computing. He is editor-in-chief of Engineering Applications of Artificial Intelligence (EAAI) and serves on the editorial board of several international journals. He received his PhD in Computer Science from Monash University, Melbourne, Australia.

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