Contemporary Topics in Molecular Immunology
H. Eisen
mar, 2013 · Springer Science & Business Media
E-kitob
234
Sahifalar soni
reportReytinglar va sharhlar tasdiqlanmagan Batafsil
Bu e-kitob haqida
Immunochemistry, recently rechristened molecular immunology, has been pre occupied throughout its long history with the structure and function of antibodies and the specificity of antibody-antigen reactions. With the recent X-ray diffrac of several crystallized immunoglobulin (Ig) fragments and a whole tion analyses Ig molecule, the three-dimensional structure of antibodies and their ligand combining sites has been realized, marking the concluding stages of a phase of immunological research that can be traced back at least 75 years. At the same time chemically minded immunologists have been moving in new directions. A substantial beginning in one direction has been made with the purification of messenger RNAs (mRNAs) for Ig chains. Hybridization of these RNAs (or their DNA copies made with the enzyme reverse transcriptase) to cell DNA is beginning to provide convincing estimates of the number of germ-line Ig genes. And some hybridization studies have already yielded suggestive evidence for translocation of V and C genes from separate to contiguous positions in DNA isolated from cells at different stages of differentiation. Moreover, in vitro trans lation of Ig mRNAs has revealed a remarkably hydrophobic stretch of about 20 amino acids at the N-terminus of the nascent Ig chain. This extra piece is absent in the Ig extracted from or secreted by plasma cells, presumably because it is rapidly cleaved from the "preimmunoglobulin" chain within the cell, but the extra piece probably plays a key role in directing the synthesis of prelg to the cell's secretory pathway.
Bu e-kitobni baholang
Fikringizni bildiring.
Qayerda o‘qiladi
Smartfonlar va planshetlar
Android va iPad/iPhone uchun mo‘ljallangan Google Play Kitoblar ilovasini o‘rnating. U hisobingiz bilan avtomatik tazrda sinxronlanadi va hatto oflayn rejimda ham kitob o‘qish imkonini beradi.
Noutbuklar va kompyuterlar
Google Play orqali sotib olingan audiokitoblarni brauzer yordamida tinglash mumkin.
Kitob o‘qish uchun mo‘ljallangan qurilmalar
Kitoblarni Kobo e-riderlar kabi e-siyoh qurilmalarida oʻqish uchun faylni yuklab olish va qurilmaga koʻchirish kerak. Fayllarni e-riderlarga koʻchirish haqida batafsil axborotni Yordam markazidan olishingiz mumkin.
