Computer Simulation in Cell Radiobiology
nov. 2013 · Lecture Notes in Biomathematics Bog 74 · Springer Science & Business Media
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This research monograph demonstrates the possible ways of using stochastic simulation for exploring cell kinetics, emphasising the effects of cell radiobiology. In vitro kinetics of normal and irradiated cells is the main subject, but some approaches to the simulation of controlled cell systems are considered as well: the epithelium of the small intestine in mice taken as a case in point. Of particular interest is the evaluation of simulation modelling as a tool for gaining insight into biological processes and hence the new inferences from concrete experimental data, concerning regularities in cell population response to irradiation. The book is intended to stimulate interest among computer science specialists in developing new, more efficient means for the simulation of cell systems and to help radiobiologists in interpreting the experimental data. The reader is expected to be acquainted with fundamentals of the theory of probability and stochastic processes. Applications are addressed to a biologically educated reader.
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