Chromatin and Disease
Tapas K. Kundu · Dipak Dasgupta
touko 2007 · Subcellular Biochemistry Kirja 41 · Springer Science & Business Media
E-kirja
458
sivuja
reportArvioita ja arvosteluja ei ole vahvistettu Lue lisää
Tietoa tästä e-kirjasta
It is more evident now than ever before that dynamic organization of human genome into nucleoprotein structure, chromatin confers the unique regulatory mechanisms for most of the cellular phenomena, which include replication, transcription, DNA repair, recombination and also apoptosis. The dynamic nature of the chromatin is regulated by chromatin modifications (epigenetic alterations), remodeling, histone chaperones and functional interactions of different chromatin interacting n- histone proteins. Dysfunction of this highly inter connected machineries disturb the cellular homoeostasis, and thereby causes several diseases. As we advance in our knowledge of chromatin function and also disease mechanisms in more details, their causal relationship is becoming more evident. This has lead to the identification of chromatin function as target for new generation therapeutics. In the light of these advances, it happens to be the right time to explore current insights into various aspect of chromatin and disease connection under one cover. Authors who are actively involved in chromatin research and have made several original contributions to develop latest paradigms in the field have written the chapters of this book. Significantly, the authors’ repertoire is truly international. They come from eight different countries of Asia, Europe and America. The book has been divided into three different parts. Part I introduces the reader to the dynamic nature of chromatin structure and its link to diseases. First two chapters in this part deal with the chromatin architecture, chromatin dynamics in the cell cycle and molecular mechanism of chromatin remodeling.
Arvioi tämä e-kirja
Kerro meille mielipiteesi.
Tietoa lukemisesta
Älypuhelimet ja tabletit
Asenna Google Play Kirjat ‑sovellus Androidille tai iPadille/iPhonelle. Se synkronoituu automaattisesti tilisi kanssa, jolloin voit lukea online- tai offline-tilassa missä tahansa oletkin.
Kannettavat ja pöytätietokoneet
Voit kuunnella Google Playsta ostettuja äänikirjoja tietokoneesi selaimella.
Lukulaitteet ja muut laitteet
Jos haluat lukea kirjoja sähköisellä lukulaitteella, esim. Kobo-lukulaitteella, sinun täytyy ladata tiedosto ja siirtää se laitteellesi. Siirrä tiedostoja tuettuihin lukulaitteisiin seuraamalla ohjekeskuksen ohjeita.
