Analysis of Pharmaceuticals by Capillary Electrophoresis
Kevin D. Altria
أبريل 2013 · CHROMATOGRAPHIA CE-Series الكتاب 2 · Springer Science & Business Media
كتاب إلكتروني
285
صفحة
reportلم يتم التحقّق من التقييمات والمراجعات. مزيد من المعلومات
معلومات عن هذا الكتاب الإلكتروني
During the 1980's the analysis of pharmaceuticals was dominated by the use of High Perfor mance Liquid Chromatography (HPLC). Other separative techniques such as Gas Chromato graphy and Thin Layer Chromatography offered alternatives but their quantitative capabili ties and/or solute range could not approach that of HPLC. The majority of pharmaceuticals are ionic and it would be reasonable to assume that electrophoresis may be useful in the analysis of pharmaceuticals. However, the electrophore tic instruments available in the 1980's were labour intensive and employed post-separation detection procedures. During the late 1980's and early 1990's extensive research was con ducted into the possibilities of conducting electrophoretic separations in capillaries. This approach allowed on-line detection and could be performed on fully automated equipment. This research led to the advent of modern day capillary electrophoresis (CE) instruments which offer similar performance and automation levels to that of HPLC. Research was also focused on developing applications for CE and particular attention was paid to applications within the pharmaceutical analysis area. These applications proved that CE could be applied to a wide range of drug types including water insoluble and neutral compounds. The ability to achieve efficient chiral separations of drugs also increased the popularity of the technique. CE with indirect UV detection has become established as a simple and effective alternative to ion-exchange chromatography for the determination of small inorganic or organic ions.
نبذة عن المؤلف
Dr. Kevin D. Altria ist Wissenschaftler bei der Glaxo Company in Großbritannien.
The author, Dr. Kevin D. Altria, has been working in Glaxo Wellcome R & D for 10 years. During this time he has developed and implemented many routine pharmaceutical analysis CE methods.
The author, Dr. Kevin D. Altria, has been working in Glaxo Wellcome R & D for 10 years. During this time he has developed and implemented many routine pharmaceutical analysis CE methods.
تقييم هذا الكتاب الإلكتروني
أخبرنا ما هو رأيك.
معلومات القراءة
الهواتف الذكية والأجهزة اللوحية
ينبغي تثبيت تطبيق كتب Google Play لنظام التشغيل Android وiPad/iPhone. يعمل هذا التطبيق على إجراء مزامنة تلقائية مع حسابك ويتيح لك القراءة أثناء الاتصال بالإنترنت أو بلا اتصال بالإنترنت أينما كنت.
أجهزة الكمبيوتر المحمول وأجهزة الكمبيوتر
يمكنك الاستماع إلى الكتب المسموعة التي تم شراؤها على Google Play باستخدام متصفح الويب على جهاز الكمبيوتر.
أجهزة القراءة الإلكترونية والأجهزة الأخرى
للقراءة على أجهزة الحبر الإلكتروني، مثل أجهزة القارئ الإلكتروني Kobo، عليك تنزيل ملف ونقله إلى جهازك. يُرجى اتّباع التعليمات المفصّلة في مركز المساعدة لتتمكّن من نقل الملفات إلى أجهزة القارئ الإلكتروني المتوافقة.
