Advanced Techniques in Antibody Generation: Antibody Engineering, Hybridoma Technology, and Phage Display

· ·
· Academic Press
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Advanced Techniques in Antibody Generation: Antibody Engineering, Hybridoma Technology, and Phage Display offers a detailed overview of the latest techniques and protocols available in antibody engineering, providing a basis for developing novel and enhanced antibody-based therapeutics for various illnesses and conditions. Early chapters focus on mechanisms and purposes of antibody production across different hosts and the structure and function of immunoglobulin molecules. The book then covers a range of aspects of antibody engineering, including antibody synthesis and screening, antibody engineering and optimization, production, and utilization.The book provides in-depth explanations of antibody engineering approaches, including phage display, hybridoma, and recombinant DNA technologies. Therapeutic, diagnostic, and biotechnological applications are also covered, providing readers with a comprehensive understanding of the methodologies discussed, and thus empowering them to effectively utilize these techniques in their own research or development initiatives. - Covers the fundamental principles of antibody engineering and its applications in various fields, including imaging, therapy, and diagnostics - Includes numerous methods and procedures utilized in antibody engineering - Explores future directions for antibody engineering and its prospective effects on healthcare

Звесткі пра аўтара

Dr. Hilal Ahmad Parray is currently a postdoctoral fellow at UT Southwestern Medical Center in Texas, USA. He obtained his PhD in Biotechnology from Daegu University, South Korea in 2018. Dr. Parray has a diverse professional background, having served as a Postdoctoral Fellow at Niigata National University in Japan and Translational Health Science and Technology Institute in India between 2018 and 2021. His specialization lies in the field of antibody engineering, utilizing hybridoma and phage display technology. Dr. Parray has a wealth of experience and is an expert in the field of monoclonal antibody-based medicinal development. His current work is mostly focused on advancing the development of antibody-based treatments, with an emphasis on viruses as dangerous pathogens. With over 40 research publications in esteemed international journals, including renowned publications such as Nature Microbiology, Dr. Parray has gained widespread recognition as a pioneering figure in his field.

Dr Kumar, Assistant Professor, Department of Biosciences, Himachal Pradesh University, Shimla (Himachal Pradesh) India has ~10 years of experience in teaching and research. His research expertise is in Physiology and Applied Zoology with research interest in alternative medicine for the treatment in Diabetes and therapeutic roles of polyphenols. He has supervised ~43 postgraduate students for their research work and was awarded a Meritorious Fellowship by the University Grants Commission, Govt of India. He has published ~140 Research Articles including 15 Book chapters and participated in more than 80 national/international conferences. He has earned 12 awards from reputed organizations for his excellent research. Dr Kumar has successfully organized many seminars/conferences and is actively involved in delivering invited talks/extension lectures at various events. He is also a reviewer of several journals of national and international repute and a Board Member of Acta Scientific and Endocrinology, Diabetes and Metabolic Complications.

Dr. Irfan A. Rather is a highly accomplished academic and researcher currently serving as an Associate Professor at King Abdulaziz University in Jeddah. Prior to this, he held the position of Assistant Professor at Yeungnam University. Throughout his career, Dr. Rather has published over 100 scientific papers in reputable journals and holds ten patents, making him a widely recognized innovator in his field. Dr. Rather's research focuses on two key areas: understanding the pathogenesis of zoonotic viruses and investigating the role of the gut microbiome in immune modulation. His extensive expertise and in-depth knowledge have enabled him to make significant contributions to these critical areas of research, helping to advance our understanding of these complex and challenging topics. Dr. Rather is widely respected in the scientific community for his contributions, which have been recognized for their exceptional quality and impact.

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