Doctored
Charles Piller
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âA seminal account of deceit that will long be remembered alongside Theranos and Enron as a scandal for the ages.â âKatherine Eban, author of Bottle of Lies and Vanity Fair special correspondent
For readers of Empire of Pain and Dopesick, an arresting deep dive into how Alzheimerâs disease treatment has been set back by corrupt researchers, negligent regulators, and the profit motives of Big Pharma.
Nearly seven million Americans live with Alzheimerâs disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Pillerâs Doctored shows that weâve quite likely been walking the wrong path to finding a cure all alongâled astray by a cabal of self-interested researchers, government accomplices, and corporate greed.
Piller begins with a whistleblowerâVanderbilt professor Matthew Schragâwhose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prizeârumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Pillerâs revelations of Schragâs findings stunned the field and the public.
From there, based on years of investigative reporting, Doctored exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimerâs research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the fieldâs institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimerâs disease, but for scientific research, funding, and oversight at large.
For readers of Empire of Pain and Dopesick, an arresting deep dive into how Alzheimerâs disease treatment has been set back by corrupt researchers, negligent regulators, and the profit motives of Big Pharma.
Nearly seven million Americans live with Alzheimerâs disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Pillerâs Doctored shows that weâve quite likely been walking the wrong path to finding a cure all alongâled astray by a cabal of self-interested researchers, government accomplices, and corporate greed.
Piller begins with a whistleblowerâVanderbilt professor Matthew Schragâwhose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prizeârumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Pillerâs revelations of Schragâs findings stunned the field and the public.
From there, based on years of investigative reporting, Doctored exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimerâs research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the fieldâs institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimerâs disease, but for scientific research, funding, and oversight at large.
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Charles Piller is an investigative journalist for Science magazine and his work has appeared in the Los Angeles Times, The New York Times, The Sacramento Bee, and more. Piller has been honored with many national journalism awards, and is the author of Gene Wars, The Fail-Safe Society, and Doctored. He has reported on public health, biological warfare, infectious disease outbreaks, and other topics from the United States, Africa, Asia, Europe, and Central America. Follow him on X @CPiller.
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